1.0 OBJECTIVE:To lay down the procedure for operation of L.O.D. oven.
2.0 SCOPE:This SOP shall be applicable to Quality Control Dept.
3.0 RESPONSIBILITY:Supervisor Quality Control
4.0 ACCOUNTABILITY:Sr. Manager Quality Assurance
5.0 PROCEDURE:5.1 Tightly close the door of the oven.
5.2 Switch on the instrument.
5.3 Set desired temperature using temperature control knob.
5.4 Allow the instrument to reach desired temperature.
5.5 Switch off the instrument, and place substance to be dried into the oven.
5.6 Close the door tightly & switch on the instrument.
5.7 Allow substance to be dried in the desired temperature for specified time period.
5.8 Switch off the oven.
5.9 Remove substance & place in a dessicator to attain Room Temperature before weighing.
5.10 If drying in vacuum is required, after step (5.6), connect vacuum pump to vacuum nozzle & allow the desired vacuum to be created, then close the vacuum knob tightly and proceed to step (5.7), maintaining the vacuum through out the drying process.
Related: Difference Between Water (Moisture) Content and Loss on Drying (LOD)
6.0 ABBREVIATIONS:6.1 SOP : Standard Operating Procedure
6.2 Dept. : Department
Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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