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Operation and Cleaning of Mechanical Sifter


Learn the operation and cleaning of Mechanical Sifter used for tablet manufacturing.

PRE-STARTUP: (IN THE BEGINNING OF SHIFT)

1.  Check the cleanliness of the room.
2.  Check the material lying in the room is of the same batch to proceed.
3.  Remove the clean status label of the equipment and tear off them after confirming the details.
4.  Put the equipment label on the machine.

AT THE TIME OF BATCH CHANGEOVER OF THE SAME PRODUCT:

1.  Check and ensure the cleanliness of the equipment / area.
2.  Put the equipment label on the machine.

AT THE TIME OF PRODUCT CHANGEOVER:

1.  Check the cleanliness of the room / equipment and ensure that the area / equipment are free from remains of the previous product.
2.  Check and ensure the availability of the rinse water analysis report and attach that in BMR.
3.  Check the room temperature and relative humidity and record it in BMR, equipment log card, if it is not within limit, inform the maintenance and do not proceed till it get rectified.

START UP:

OPERATION:

1.  Check and ensure the cleanliness and integrity of the sieves. Ensure that they are properly fixed to the equipment as per the product specification.
2.  Check and ensure the cleanliness of dedicated scoops used for pouring the material.
3.  Transfer the raw material to be sifted near the equipment.
4.  Transfer the cleaned in-process container near to the sifter and attach the inlet of the container to the discharge chute of the sifter.
5.  Connect the plug of the equipment to the main power supply.
6.  Switch ON the main power supply and run the machine.

SHUTDOWN:

1.  Switch OFF the main power supply.
2.  Disconnect the plug from the main power supply.

CLEANING:-

DAY’S END CLEANING:

1.  Remove loosely stucked powder from the machine by using vacuum cleaner, duster and lint free cloth.
2.  Dismantle the machine in the following sequence and keep them on pallet-
A.  Upper lid.
B.  Upper feeding
C.  Stainless Steel clamps
D.  Sieves
E.  Lower feeding hopper.
3.  Clean the dismantled parts by using vacuum cleaner, duster and lint free cloth.
4.  Clean the machine and dismantle parts with a dry lint free cloth.
5.  Clean the room as per SOP.
6.  Assemble the cleaned dismantled parts.
7.  After cleaning affix the cleaned status label on the equipment.
8.  Record the cleaning details in the equipment log card.

CLEANING AT THE TIME OF BATCH CHANGEOVER / SAME PRODUCT OF ASCENDING POTENCY:

1.  Remove loosely stucked powder from the machine by using vacuum cleaner, duster and lint free cloth.
2.  Dismantle the machine in the following sequence and keep them on pallet-
A.  Upper lid.
B.  Upper feeding
C.  SS clamps
D.  Sieves
E.  Lower feeding hopper.
3.  Clean the dismantled parts by using vacuum cleaner, duster and lint free cloth.
4.  Clean the machine and dismantle parts with a dry lint free cloth.
5.  Clean the room as per SOP.
6.  Assemble the cleaned dismantled parts.
7.  After cleaning affix the cleaned status label on the equipment.
8.  Record the cleaning details in the equipment log card.

Related: SOP for Product Changeover in Manufacturing

CLEANING AT THE TIME OF PRODUCT CHANGEOVER / SAME PRODUCT OF DESCENDING POTENCY / PREVENTIVE MAINTENANCE OF THE CONTACT PARTS:

1.  Remove loosely stucked powder from the machine by using vacuum cleaner, duster and lint free cloth.
2.  Dismantle the machine in the following sequence and keep them on pallet-
A.  Upper lid.
B.  Upper feeding
C.  SS clamps
D.  Sieves
E.  Lower feeding hopper.
3.  Clean the dismantled parts by using vacuum cleaner, duster and lint free cloth.
4.  Clean the machine and dismantle parts with a dry lint free cloth.
5.  Clean the room as per SOP.
6.  Assemble the cleaned dismantled parts.
7.  After cleaning affix the cleaned status label on the equipment.
8.  Record the cleaning details in the equipment log card.
Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
Email: .moc.enilediugamrahp@ofni Need Help: Ask Question


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