SOP for Cleaning of Gas Chromatograph (Head Space) : Pharmaceutical Guidelines

SOP for Cleaning of Gas Chromatograph (Head Space)

Standard operating procedure to clean the head space gas chromatograph.

1.0 OBJECTIVE

To lay down the procedure for cleaning of Head space gas chromatograph.

2.0 SCOPE

This procedure is applicable to clean the gas chromatograph, installed in quality control department.

3.0 RESPONSIBILITY

3.1 Doing : Technical Assistant ,Executive
3.2 Checking : Executive/Manager

4.0 ACCOUNTABILITY

Head of the Department

5.0 PROCEDURE

5.1 Switch ‘OFF ’ the instrument.
5.2 Switch ‘OFF’ the Mains.
5.3 Clean the outer surface of the instrument with dry clean cotton cloth.
5.4 Wash the syringe with distilled water for several times.
5.5 Flush the column with carrier gas for stabilization of column.
5.6 Clean the headspace auto sampler vial with D.M.water for several times and dry the vial in oven for further use.

6.0 ABBREVIATIONS

6.1 SOP - Standard Operating Procedure
6.2 D.M.water = Demineralise water



Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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