Preparation and Standardization of 0.02 M Cupric Sulphate | Pharmaguideline
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  • Sep 24, 2010

    Preparation and Standardization of 0.02 M Cupric Sulphate

    Preparation and standardisation of 0.02 M Cupric Sulphate solution using Disodium Edetate and Pyridylazonaphthol solution as indicator that is used in pharmaceutical analysis.

    Cupric Sulphate Solution Preparation

    • Dissolve 5.0 g of cupric sulfate in water and dilute to 1000 ml with water.
    • Standardize the solution in the following manner.

    Cupric Sulphate Solution Standardization

    • To 20.0 ml add 2 g of sodium acetate.
    • Titrate with 0.02 M disodium edetate, using 0.1 ml of pyridylazonaphthol solution as an indicator, until the color changes from violet-blue to bright green, adding the titrant slowly towards the end-point.
    • 1 ml of 0.02 M disodium edetate is equivalent to 0.004994 g of CuSO4.5H2O.
    Also see: Determination of Shelf Life of Solutions in Laboratory

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