Preparation and Standardization of 0.05 M Barium Chloride | Pharmaguideline
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  • Sep 24, 2010

    Preparation and Standardization of 0.05 M Barium Chloride

    Preparation and standardisation of 0.05 M Barium Chloride solution using Disodium edetate and Metalphthalein as indicator used in pharmaceutical analysis.

    Barium Chloride Solution Preparation

    • Dissolve 12.2 g of barium chloride in sufficient water to produce 1000 ml.
    • Standardize the solution in the following manner.

    Barium Chloride Solution Standardization

    • To 10.0 ml of the solution add 60 ml of water, 3 ml of strong ammonia solution and 0.5 to 1 mg of metalphthalein as an indicator.
    • Titrate with 0.05 M disodium edetate. 
    • As the solution begins to decolorize, add 50 ml of ethanol (95 %) and titrate until the bluish violet color is discharged.
    • 1 ml of 0.05 M disodium edetate is equivalent to 0.012215 g of BaCl2.2H20.
    Also see: Determination of Shelf Life of Solutions in Laboratory

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