Showing posts with label Troubleshooting. Show all posts
Apr 11, 2025

Resolving API Impurity Issues in Drug Development

Active pharmaceutical ingredients are the main part of every pharmaceutical product because these are the active content in any drug formula...
Apr 10, 2025

Investigation of OOS Results in Analytical Testing

It is important to maintain product quality in the pharmaceutical industry. Product quality, safety and efficacy are ensured by adherence to...
Apr 9, 2025

Strategies for Resolving Stability Issues in Drug Formulations

The stability of pharmaceutical products plays an important role in the effectiveness of drug products and patient safety. An unstable pharm...
Apr 8, 2025

Equipment Failure in Pharmaceutical Manufacturing

Pharmaceutical industry has great expectations and opportunities because medicines play an important role in everyone’s life. The pharmaceut...
Apr 7, 2025

Contamination Issues in Pharmaceutical Production and their Prevention

Contamination is one of the biggest problems in pharmaceutical industry, especially in sterile pharmaceutical manufacturing. It is very impo...
Aug 21, 2024

How to Care for pH Meter Electrodes

pH meter electrodes measure the degree of acidity by comparing the aqueous solutions. The electrodes are immersed in with the reference half...
Apr 3, 2024

10 Tips for HPLC Analysis In Pharmaceuticals

HPLC, also known as High-Performance Liquid Chromatography system , is one of the most crucial analytical methods in pharmaceuticals. The pu...
Mar 5, 2024

Tablet Defects in Pharmaceutical Manufacturing

Defected tablets are the most common problem in pharmaceutical manufacturing. These defects may occur in any stage of manufacturing from raw...
Sep 13, 2020

Top 10 Tips for Microbial Limit Test

The microbial limit test is the quantitative and qualitative assessment of the microbes or microbial contamination test in a sample. This te...
Oct 13, 2019

Problems Associated with Pharmaceutical Cleanroom Areas

Pharmaceutical cleanroom areas are used to protect pharmaceutical products from pollutants that cause undesired contamination in pharmaceuti...
Jun 2, 2019

Causes and Remedies of Picking in Tablet Manufacturing

In the pharmaceutical world, tablet picking refers to when a portion of the material in a tablet is removed. In most cases, picking occurs o...
Sep 27, 2018

Manufacturing of Tablets by Direct Compression Method

In the past years, the processing of drugs was mostly achieved through wet granulation or related unit operations. Progressively, other meth...
Aug 6, 2018

Causes and Remedies of Chipping in Tablet Manufacturing

Innovations in the tablet manufacturing process have seen the dawn of machine operations in the manufacture of tablets. While it would have ...
Feb 11, 2018

Causes and Remedies of Binding in Tablet Manufacturing

Tablet manufacturing involves a series of processes all aimed at the result of a uniform fine piece of art tablet. This article aims at expl...
Jan 21, 2018

Causes and Remedies of Sticking in Tablet Manufacturing

The tablet production process has become more simplified and more mechanized with the development of technology. However, the complexity of ...
Dec 3, 2017

Causes and Remedies of Cracking in Tablet Manufacturing

Cracking is a situation in which small cracks are identified on the top and bottom central surfaces of tablets during the processing of the...
Nov 26, 2017

Causes and Remedies of Lamination in Tablet Manufacturing

An ideal tablet should be free from any visual defects as well as the functional defects. Despite the advancements and innovations in the m...
Nov 5, 2017

Causes and Remedies of Capping in Tablet Manufacturing

When the top of a tablet separates from rest of its body, it is called tablet capping. It happens when the air in the tablet is not being r...
Sep 13, 2017

Types and Functionality of Tablet Coating

Tablet coating is the outer covering of a tablet with a layer/substance. The coats used range from the traditional sugar coating to the pres...
Sep 9, 2017

Compression Defects and Corrective Actions

1. All defects have observed during an inspection of compression machine will be classified with the following category: Critical: Those d...