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SOP for Out of Acceptance Limit for Critical Parameters in Purified Water System


Standard operating procedure to take the action when any critical parameter is found out of specification in purified water system.

1.0 OBJECTIVE:

      To lay down procedure for actions to be taken in case of out of acceptance limit for critical parameters in purified water system.

2.0 SCOPE:

      This SOP shall be applicable for purified water generation and distribution system.

3.0 RESPONSIBILITY:

      Operator/Engineer/Executive

4.0 ACCOUNTABILITY:

      Head of Engineering

5.0 PROCEDURE: 

5.1 SOFT WATER HARDNESS

5.1.1 If soft water hardness exceeds 5.0 PPM.
5.1.1.1 Stop the RO system and close the RO inlet valve.
5.1.1.2 Drain the water from soft water storage tank.
5.1.1.3 Check the functioning of softener unit for regeneration.
5.1.1.4 Regenerate the softener unit manually and again check the hardness.
5.1.1.5 If hardness found within the limit collect the water in soft water storage tank and restart RO system.

5.2 pH

5.2.1 If pH of water before RO found below 7.5, increase the Sodium Hydroxide (NaOH) solution dosing.
5.2.2 If pH of water before RO found above 8.0, decrease the Sodium Hydroxide (NaOH) solution dosing.

5.3 PRESSURE DROP ACROSS MICRON CARTRIDGE FILTER (MCF)–1 MICRON

5.3.1 If the pressure drop across MCF exceeds 0.8 kg / cm2, replace the MCF.

5.4 ORP VALUE

5.4.1 If ORP value exceeds 350 mv.
5.4.1.1 Check the free chlorine present in the water at the outlet of softener (This is checked by Free Chlorine Test Kit).
5.4.1.2 If it is found more than 2 ppm, reduce the chlorine dosing to get 2 ppm at the outlet of Softener and follow the steps 5.5.1.4 to 5.5.1.7
5.4.1.3 If it is 2 ppm, no need to adjust chlorine dosing. Adjust the SMBS dosing to ensure that chlorine is absent before RO.
5.4.1.4 Stop soft water pump.
5.4.1.5 Drain water from soft water tank.
5.41.6 Collect the fresh soft water in soft water tank.
5.4.1.7 Start soft water pump & SMBS dosing.

5.5 RO CONDUCTIVITY

5.5.1 In case of RO conductivity exceeds 30 μS / cm.
5.5.1.1 Check the RO feed water hardness
5.5.1.2 Check the RO feed water pressure which should not be beyond the limit i.e.5.0 to 9.0 kg/cm2.
5.5.1.3 Check the port ‘O’ rings of RO membranes.

5.6 RO FEED PRESSURE 5.0 to 9.0 Kg / cm2

5.6.1 If the RO feed pressure found beyond 5.0 to 9.0 kg/cm2.
5.6.1.1 Check the RO membranes for rupture. If rupture is found, replace the RO membranes.
5.6.1.2 Check the RO membranes for fouling. If fouling is found, do the chemical cleaning for RO membranes.

5.7 EDI CONDUCTIVITY

5.7.1 If the EDI conductivity exceeds beyond 1.0 μS/cm, Check the EDI feed water conductivity (Refer step No.5.5).

5.8 DISTRIBUTION CONDUCTIVITY

5.8.1 If the distribution conductivity exceeds 1.0 μS/cm.
5.8.1.1 Drain the water from storage tank.
5.8.1.2 Drain water from all user points, all sampling points, and pump drain.
5.8.1.3 Collect the fresh water in the storage tank.
5.8.1.4 Again check the conductivity of water from the storage tank.
5.8.1.5 If the conductivity is still higher than the specified limit, do the hot water sanitization of storage tank and distribution system.

5.9 U.V. TUBE INTENSITY – 2.4 MW / CM 2

5.9.1 If the UV tube intensity is less than 2.4 MW / cm 2, replace the UV tubes.

6.0 ABBREVIATION:

6.1 SOP : Standard Operating Procedure

Also see: Purified Water System
Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
Email: .moc.enilediugamrahp@ofni Need Help: Ask Question


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