Learn how to determine the Foreign Organic Matter in Pharmaceutical samples.
MethodWeigh 100 to 500 g, or the quantity specified in the individual monograph, of the original sample and spread it out in a thin layer. Inspect the sample with the unaided eye or with the use of a 6x lens and separate the foreign organic matter manually as completely as possible. Weigh and determine the percentage of foreign organic matter from the weight of the drug taken. Use the maximum quantity of sample for coarse or bulky drugs.
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