SOP for Cleaning of Vacuum Oven : Pharmaceutical Guidelines

SOP for Cleaning of Vacuum Oven

Standard operating procedure to clean the vacuum oven used for determination of LOD.


To clearly lay down procedure for cleaning .


This procedure is applicable for vacuum oven installed at, quality control laboratory.


3.1 Doing : Technical Assistant
3.2 Checking : Executive/Manager


Head of the Department


5.1 After completion of the testing, switch ‘OFF ’ the instrument.
5.2 Release the vacuum carefully and slowly with pressure regulator till zero pressure observed in pressure gauge.
5.3 Allow the oven to cool down to room temperature.
5.4 Loose the screw of door carefully and open the door, take out the LOD bottles and put into desiccator.
5.5 Remove any solid or unlabeled waste items from the oven.
5.6 Remove the self from the oven and clean with cotton cloth
5.7 Clean the inner surface of the oven with clean dry cloth.
5.8 Keep the self into its respective place.
5.9 Switch on the instrument and set the temperature as per operating procedure


6.1 SOP - Standard Operating Procedure
6.2 LOD - Loss on drying

Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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