To check performance of the equipment for reliable and accurate results.
This procedure is applicable to check performance of the atomic absorption spectrophotometer installed in quality control department.
3.1 Doing : Technical Assistant
3.2 Checking : Executive /Manager
Head of the Department
Frequency : Once in a month
5.1 Operate the instrument as per respective standard operating procedure.
5.2 Use Cu standard for radiations.
5.3 Prepare 0.5 mcg/ml, 1.0 mcg/ml, 1.5 mcg/ml, 2.0 mcg/ml and 2.5 mcg/ml in water.
5.4 Aspirate the above solution and measure the absorbance.5.5 Calculate the correlation coefficient by the instrument/computer.
5.6 Correlation coefficient should not less than 0.9900 %.
5.7 The performance of the instrument is satisfactory if the obtained correlation coefficient is within the given limit otherwise follow the S.O.P.
6.1 % = Percentage
6.2 mcg= microgram
6.3 ml= millilitre
6.4 cu= copper
PERFORMANCE CHECK REPORT OF ATOMIC ABSORPTION
PERFORMANCE CHECK DATE
DATE OF LAST PERFORMANCE CHECK DONE
NEXT DUE FOR
Test % w/v
Correlation coefficient : _________ (Limit : Not less than 0.9900 %)
Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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