SOP for Cleaning of Three Piece Filling Machine Parts and Silicon Tubing : Pharmaceutical Guidelines

SOP for Cleaning of Three Piece Filling Machine Parts and Silicon Tubing

Standard operating procedure of Three Piece vial Filling Machine.

1.0 PURPOSE:

This document deals with the procedure for cleaning of Three Piece Filling machine parts and silicon tubing.

2.0 SCOPE:

Applicable to Three Piece vial Filling Machine.

3.0 RESPONSIBILITY:

Production Staff

4.0 ACCOUNTABILITY:

Head of Department

5.0 PROCEDURE:

5.1 Switch off the mains of filling and sealing machine.
5.2 Remove the syringe and silicon tubing from machine in the SS tray.
5.3 Dismantle the nozzle, valve, piston and silicon tubing of syringe.
5.4 Flush fill nozzle, valves, piston and silicon tubing each with 5 L of hot DW.
5.5 Repeat step 5.4 with another 5 L of DW.
5.6 Repeat step 5.4 with another 1 L of DW.
5.7 Repeat step 5.3 to 1.6 for other 3 sets of fill nozzle and syringe.
5.8 Assemble syringe and put in filling machine parts tray.
5.9 Autoclave the machine parts at 121°C for 30 mins. as per SOP.

6.0 ABBREVIATIONS:

DW : Distilled Water
L : Litre
Mins : Minutes
°C : Degree Centigrade





Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
.moc.enilediugamrahp@ofni :liamENeed Help: Ask Question


Click Here

No comments:

Post a Comment

CURRENT JOBS

Show All ❭❭Jobs by PharmaJobs

Write a Powerful CV

Click Here

Advertise Here

Get App for News Updates

Scan to Download

Android App
Android App

Recent Posts