To study heat distribution in the chamber of DHS using probes with data logger.
To ensure proper heat distribution in the chamber of dry heat sterilizer with load using data logger.
3.1 Doing : Engineering department
3.2 Checking : Executive /Manager
Head of the Department
Frequency : Once in a Year
5.1 Load the DHS with the glassware and accessories to be sterilized.
5.2 Put six calibrated flexible probes in the DHS as per location chart attached.5.3 Connect the flexible probes to the recorder of data logger & set the record interval 10 minute.
5.4 Operate the DHS as per SOP.
5.5 Note down the validation parameters and sterilization cycle details like time,temperature etc. in annexure – I.
5.6 After completion of DHS cycle, note down the hottest location and coldest location in temperature record for DHS in annexure II .
5.7 Record the reading of each probe temperature kept inside DHS and temperature on digital temperature indicator at every 10 minute interval in annexure –II till completion of sterilization cycle.
5.8 Attach the data logger print out with Annexure II data.
Acceptance criteria : Temperature at each point must reach 180 °C +10 °C.
6.1 oC = Degree centigrade
6.2 DHS= Dry heat sterilization
Heat distribution study in DHS with load
(A) Validation parameters
(1) Sterilization time :
(2) Set temperature :
(B) Cycle details
(1) Cycle start time :
(2 Temperature achieved :
(3) Time of temperature Achieved :
(4) Sterhold started at :
(5) Sterhold completed at :
(6) Cycle completed at :
( C ) Load details :
Microbiologist QA Dept
Dept Q.C. Manager Eng.
Heat distribution study in DHS with load Temperature records( Temperature to be recorded every 10 min.)
Temperature of probes at Location
Conclusion and results :
Location no. ________ is the hottest location in the DHS.
Location no ._________ is the coldest location in the DHS .
Microbiologist Q.A.Dept. Engineering dept. Q.C. Manager
Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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