Calibration of Refractometer | Pharmaguideline
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  • Apr 17, 2021

    Calibration of Refractometer

    Learn how to verify the performance of Refractometer using Distilled Water, Toluene and Carbon Tetrachloride as standard.

    PROCEDURE

    Calibrate the apparatus using following solvents:
    Name of the Liquid
    Refractive Index
    Temperature
    Distilled Water
    1.3325
    20°C ± 0.5°C
    Toluene
    1.4969
    20°C ± 0.5°C
    Carbon Tetrachloride
    1.4603
    20°C ± 0.5°C
    Requirement: Tolerance: ± 0.0005
    Frequency: Once in a month.
    Maintenance/ Repairs: When the instrument does not comply with the requirement/ tolerance range specified above, the instrument should be labeled “OUT OF CALIBRATION” and should be repaired/ serviced.
    Reference: Operator’s instructions manual.

    QUALITY ASSURANCE DEPARTMENT
    CALIBRATION REPORT OF REFRACTOMETER
    Reference : 
    Date -
    Frequency -
    Instrument No. - 
    Make – 
    Model – 

    Sr. No.
    Name of the Liquid
    Observed Refractive Index
    20°C ± 0.5°C
    Acceptance criteria
     Refractive Index
    20°C ± 0.5°C
    1
    Distilled Water
    1.3320 to 1.3330
    2
    Toluene
    1.4964 to 1.4974
    3
    Carbon Tetrachloride
    1.4598 to 1.4608
    Conclusion :
    Calibration complies/ does not comply as per the acceptance criteria.
    Next calibration due on :
    Done  By :
    Date :
    Checked By :
    Date :

    2 comments: Post Yours! Read Comment Policy ▼

    1. Thanks for taking time for sharing this article, it was excellent and very informative. It’s my first time that I visit here. I found a lot of informative stuff in your article. Keep it up. Thank you.

      ReplyDelete
    2. Very good information & So simple that can be easily implemented.

      ReplyDelete

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