SOP for Cleaning of Fourier Transform Infrared Spectrophotometer

Standard operating procedure to clean the Fourier Transform Infrared Spectrophotometer.

1.0 OBJECTIVE

To clearly lay down procedure for cleaning of fourier transform infrared spectrophotometer.

2.0 SCOPE

This procedure is applicable to clean the fourier transform spectrophotometer installed in quality control department.

3.0 RESPONSIBILITY

3.1 Doing : Technical Assistant/Executive
3.2 Checking : Executive/Manager

4.0 ACCOUNTABILITY

Head of the Department

5.0 PROCEDURE

5.1 Clean the instrument with clean cloth.
5.2 For DRS system
5.2.1 After each I.R , discard the sample and wipe the sample cap with tissue paper.
5.3 For liquid samples
5.3.1 After each IR ,wash the KBr pellet with carbon tetrachloride.
5.4 Switch ‘OFF’ the instrument and wipe it with clean cotton cloth.
5.5 Record in the format of instrument log card.

Related: Calibration of FTIR

6.0 ABBREVIATIONS

6.1 I.R = Infra red
6.2 S.O.P. = Standard operating procedure
6.3 KBr= Potassium Bromide
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is a prominent Pharmaceutical Quality Assurance expert, consultant and the founder of Pharmaguideline. With over 22 years of hands-on experience in cGMP-compliant manufacturing environments, he specializes in establishing validation protocols, sterile area controls and data integrity systems. Ankur routinely interprets international regulatory frameworks (including FDA, EMA and ICH guidelines) to help global pharmaceutical professionals ensure strict regulatory compliance and operational excellence. Connect with Ankur on LinkedIn. Need Help: Ask Question

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