SOP for Cleaning of Metrohm Karl Fisher : Pharmaceutical Guidelines

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SOP for Cleaning of Metrohm Karl Fisher

Standard operating procedure to clean the Metrohm karl Fisher.

1.0 OBJECTIVE

To clearly define the cleaning of Metrohm Karl fisher.

2.0 SCOPE

This procedure is applicable to karl fisher installed in quality control laboratory.

3.0 RESPONSIBILITY

3.1 Doing : Technical Assistant
3.2 Checking : Executive /Manager

4.0 ACCOUNTABILITY

Head of the Department

5.0 PROCEDURE

5.1 Before switching ‘ON’ the instrument wipe the instrument with cloth.
5.2 On completion of the titration, Press ‘Out’ at the rear side of the Ti stand to drain out the solvent from
the titration vessel.
5.3 Press ‘In’ at the rear side of Ti stand to fill the vessel with Methanol.
5.4 Again drain off the methanol.
5.5 Switch off the instrument
5.6 After switch off the instrument, clean the instrument with cotton cloth.

Related: Calibration of Karl Fischer Apparatus

6.0 ABBREVIATION

6.1 SOP - Standard Operating Procedure
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Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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