SOP for Cleaning of Vertical Autoclave

Standard operating procedure to clean the vertical autoclave.

1.0 OBJECTIVE

To define the cleaning procedure.

2.0 SCOPE

This procedure is applicable for cleaning of Vertical Autoclave, installed in Micro Dept.

3.0 RESPONSIBILITY

3.1 Doing: Workman / Technical Assistant
3.2 Checking: Technical Assistant / Executive

4.0 ACCOUNTABILITY

Head of the Department

5.0 PROCEDURE

5.1 After completion of the cycle, switch off the instrument & mains.
5.2 Place a vessel below the drain valve provided at the bottom.
5.3 Open the drain valve to clean the chamber.
5.4 Clean the inner surface with a clean dry cotton cloth.
5.5 Record it in Annexure - I.

Related: Autoclave Validation

6.0 ABBREVIATIONS 

6.1 SOP - Standard Operating Procedure

ANNEXURE-I
MICROBIOLOGY LAB – Q.C.
CLEANING RECORD OF VERTICAL AUTOCLAVE

Date
Inner side
Outer side
Cleaned By
Checked By


































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is a prominent Pharmaceutical Quality Assurance expert, consultant and the founder of Pharmaguideline. With over 22 years of hands-on experience in cGMP-compliant manufacturing environments, he specializes in establishing validation protocols, sterile area controls and data integrity systems. Ankur routinely interprets international regulatory frameworks (including FDA, EMA and ICH guidelines) to help global pharmaceutical professionals ensure strict regulatory compliance and operational excellence. Connect with Ankur on LinkedIn. Need Help: Ask Question

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