Pharmaguideline

Beckmanns Rearrangement An oxime-based reaction that can result in either nitriles or amides, depending on the starting material, is the Bec...

Oppenauer Oxidation A selective oxidation is used in Oppenauer oxidation to convert secondary alcohols to ketones. Oppenauer is named for th...

Wolff Kishner Reduction A Wolff-Kishner reduction takes place when a carbanion is formed from a hydrazone anion that has released an atom of...

Birch Reduction It occurs when aromatic molecules with benzene rings are transformed into 1,4-cyclohexadiene molecules with two hydrogen ato...

Clemmensen Reduction Using hydrochloric acid and zinc amalgam, the Clemmensen reaction converts aldehydes or ketones to alkanes. Danish chem...

Metal Hybrid Reduction Reduction of aldehydes and ketones Aldehydes and ketones can be reduced to alcohols, hydrocarbons, and amines. Carbon...

Azepines Synthesis Tributylphosphine is used to deoxygenate nitrobenzene. When 2-alkoxy-3H-azepines are rearranged intramolecularly with pri...

Purine Synthesis Traube synthesis - 4-Amino-6-hydroxypyrimidine or 4-diaminopyrimidine is first nitrosated at the 5-position, followed by n...

Pyrimidine Synthesis Using phosphorus pentasulfide and triethylamine in chloroform, N,N-di-formyl aminomethyl aryl ketones are converted to ...