SOP for Cleaning of Sampling Equipment

Standard operating procedure to clean the sampling equipment.

1.0 OBJECTIVE

To lay down the procedure for cleaning of sampling equipment.

2.0 SCOPE

This SOP is applicable to the procedure for cleaning of sampling equipment.

3.0 RESPONSIBILITY

Officer/ Executive - Quality Control

4.0 ACCOUNTABILITY

Manager – Quality Control

5.0 PROCEDURE

5.1 For Scoops/ Spoons

5.1.1 Clean the sampling devices with running tap water followed by TEEPOL/LABOLENE 0.5 % soap solution to remove adhering material.
5.1.2 Finally rinse with purified water.
5.1.3 Check the cleanliness physically and clean again if it is necessary.
5.1.4 Dry in a hot air oven at 60 °C ± 5°C for 30 minutes.
5.1.5 Put the clean and dried equipment in a poly-bag and keep it at appropriate place.

5.2 For sampling pipettes (Glass)

5.2.1 Clean the equipment with running tap water followed by TEEPOL/LABOLENE 0.5 % soap solution to remove adhering material and rinse.
5.2.2 Finally rinse with purified water.
5.2.3 Check the cleanliness physically and clean again if it is necessary.
5.2.4 Keep the washed tubes for draining on the stand meant for the same.
6.2.5 After the tubes are dried the ends are covered with poly-bags.

5.3 For sampling rods (Stainless Steel)

5.3.1 Clean the things with running tap water followed by TEEPOL/LABOLENE 0.5 % soap solution to remove obvious adhering particles.
6.3.2 Finally rinse with purified water.
6.3.3 Check the cleanliness physically and clean again if required
6.3.4 Wrap the clean and dried equipment in a poly-bag & keep it in appropriate place.
6.4 After cleaning record to be maintained.
6.5 After cleaning sampler can be used with in 48 hours.

6.0 ABBREVIATIONS

6.1 SOP - Standard Operating Procedure
6.2 No. - Number
6.3 QA - Quality Assurance
6.4 CCF - Change control format
6.5 NA - Not applicable
6.6 QC - Quality Control
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is a prominent Pharmaceutical Quality Assurance expert, consultant and the founder of Pharmaguideline. With over 22 years of hands-on experience in cGMP-compliant manufacturing environments, he specializes in establishing validation protocols, sterile area controls and data integrity systems. Ankur routinely interprets international regulatory frameworks (including FDA, EMA and ICH guidelines) to help global pharmaceutical professionals ensure strict regulatory compliance and operational excellence. Connect with Ankur on LinkedIn. Need Help: Ask Question

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