SOP for Calibration of Thermometer in Pharma : Pharmaceutical Guidelines

SOP for Calibration of Thermometer in Pharma

Standard operating procedure to calibrate the thermometer using reference standards having standard melting range.

1.0 OBJECTIVE

To lay down the procedure for calibration of Thermometer.

2.0 SCOPE

This SOP shall be applicable to Quality Control Dept.

3.0 RESPONSIBILITY

Quality Control Supervisor

4.0 ACCOUNTABILITY

Sr. Manager Quality Assurance

5.0 PROCEDURE

5.1 Each thermometer shall be numbered and identified by its number whenever it is used, either for calibration or for routine temperature measurements. These thermometers are calibrated using following reference standards for their accuracy and record:
Sr. No.
Substance
Standard Thermometer
Reading
Standard Melting Range
1.
Vanillin

81 – 83°C
2.
Acetanilide

114 – 116°C
3.
Sulphanilamide

164.5 –166.5°C
4.
Caffeine

234 – 237°C
Any thermometer that breaks or does not respond to given temperature range should be discarded.

6.0 ABBREVIATION

6.1 SOP: Standard Operating Procedure

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Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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