SOP for Cleaning of Karl Fischer Apparatus : Pharmaceutical Guidelines

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SOP for Cleaning of Karl Fischer Apparatus

Standard operating procedure to clean the karl fischer apparatus.

1.0 OBJECTIVE

To clearly lay down the procedure for cleaning.

2.0 SCOPE

This procedure is applicable to Karl Fischer apparatus, installed in quality control laboratory.

3.0 RESPONSIBILITY

3.1 Doing: Technical Assistant
3.2 Checking: Executive/Manager

4.0 ACCOUNTABILITY

Head of the Department

5.0 PROCEDURE

5.1 After completion of the testing, press FLUSH switch for flushing of Karl Fischer reagent into a storage bottle.
5.2 Remove the solution from the test compartment and wash with methanol which is used for water determination. Wipe the knob of sample compartment with tissue paper.
5.3 Switch ‘OFF’ the instrument and switch ‘OFF’ the mains.
5.4 Collect the waste solution into the waste beaker at the same time all waste to be thrown to avoid corrosion.
5.5 Clean the outer surface of the instrument with isopropyl alcohol and dry it with tissue paper.
5.6 Keep the record in the log card of instrument

6.0 ABBREVIATION

6.1 SOP - Standard Operating Procedure
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Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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