SOP for Cleaning of Gas Chromatograph (Head Space) : Pharmaceutical Guidelines

SOP for Cleaning of Gas Chromatograph (Head Space)

Standard operating procedure to clean the head space gas chromatograph.

1.0 OBJECTIVE

To lay down the procedure for cleaning of headspace gas chromatograph.

2.0 SCOPE

This procedure is applicable to clean the gas chromatograph, installed in the quality control department.

3.0 RESPONSIBILITY

3.1 Doing: Technical Assistant, Executive
3.2 Checking: Executive/Manager

4.0 ACCOUNTABILITY

Head of the Department

5.0 PROCEDURE

5.1 Switch ‘OFF ’ the instrument.
5.2 Switch ‘OFF’ the Mains.
5.3 Clean the outer surface of the instrument with a dry clean cotton cloth.
5.4 Wash the syringe with distilled water for several times.
5.5 Flush the column with the carrier gas for stabilization column.
5.6 Clean the headspace autosampler vial with D.M.water for several times and dry the vial in the oven for further use.

6.0 ABBREVIATIONS

6.1 SOP - Standard Operating Procedure
6.2 D.M.water = Demineralise water





Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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