Glass containers are often used in pharmaceuticals because they offer some important benefits that other materials don’t offer. They are formed by blowing, drawing, pressing, and casting. Some advantages of glass containers are there that make them fantastic option for pharmaceutical uses.
RODAC Plates and Their use in Pharmaceuticals
RODAC is an abbreviation of Replicate Organism Detection and Counting. It is usually used for surface sample testing. It is an agar, poured in a contact plate and pressed flat so that the organisms can stick to its medium. It should also be refrigerated at a 40 degree Fahrenheit and make sure that it does not get frozen. The agar is 50 millimeters in diameter and is also in the shape of a dome.
Visual Inspection of Light Sensitive Products
The pharmaceutical industry is dynamic by nature. Products in this industry are in a constant state of improvement and analysis. To keep the industry standards high, pharmaceutical products must be constantly checked for quality. One such area involves the visual inspection of light-sensitive products.
Difference between Recall and Mock Recall
Any product which is manufactured on a large scale sometimes has to go through the process of recall and mock recall. To some people, these two terms seem to be really confusing or some people don't even know the meanings of them.
How Does Quality Cost Less in Long Term?
Have you ever wondered why high-quality products or goods last longer than the low-quality ones? Do you know the reason why the rich buy quality products and still remain rich? Have you ever thought of internalizing the saying "cheap is expensive"? Well, in this article you will be able to distinguish the different factors that show how does quality cost less in long-term.
Why do HEPA Filters have 0.3 Micron Pore Size?
Industrial HEPA filters or High-Efficiency Particle Air filters are an essential part of the pharmaceutical and healthcare industries, where sterile environments are mandatory. Particles that cannot be seen by the naked human eye fill the air. These minute particles can cause the development of problems when working with new medicines and medical equipment as well as carrying airborne disease.
Why do We Expose Media Plates for 4 Hours in Cleanroom Areas?
A media plate, also known as a settling plate is basically a Petri dish that contains agar medium which acts as a growth medium for microorganisms. It is commonly used in pharmaceutical companies to assess the level of microorganisms in their clean rooms in order to maintain a clean environment.
Difference Between Disinfectants and Antiseptics
Disinfectant and antiseptics are widely used for cleaning in both health care settings and also in homes. These products contain various chemical components, a majority of which have been used as cleaning agents for ages. It's a fact that they are both used for destroying disease-causing microorganisms which may lead people to think that they are the same. But the truth is that they are very …
Manufacturing of Tablets by Direct Compression Method
In the past years, the processing of drugs was mostly achieved through wet granulation or related unit operations. Progressively, other methods emerged that revolutionalized and gradually replaced the old tablet manufacturing methods. Amongst the new techniques, the direct compression method uses the most advanced technology.
Importance of Visual Inspection in Pharmaceutical Manufacturing
Pharmaceutical manufacturing industries are the most precise and quality improving industries in the world. Their main aim is to manufacture high-quality medicine products which are closely related to the health of people to heel them. But the most important in pharmaceutical manufacturing industries is quality.
Effect of Humidity Level on Tablet Stability
The level of humidity greatly affects the stability of tablets. Tablets and capsules are protected for moisture by their packing. Degradation of tablets and capsules starts when they get a high moisture content and this also appears in their physical appearance too. There are different ways through which tablet stability is affected as discussed in this article.
Don’t Know an Answer during Interview? 8 Powerful Tips to Tackle the Situation
The word ‘Interview’ comes from a Middle French phrase “s'entrevoir” which means "to see each other, visit each other briefly, have a glimpse of," and that is exactly what interviews are about. The interviewer wants to have a brief look at your capabilities and hence, tests you mentally in all possible ways. More often than not, the discomfort comes from the lack of a cohesive answe…
Causes and Remedies of Chipping in Tablet Manufacturing
Innovations in the tablet manufacturing process have seen the dawn of machine operations in the manufacture of tablets. While it would have been thought that the machines would produce perfect tablets, but that is far from the truth. Chipping is the breaking of the edges of the tablet during the manufacturing process and for chipping to occur it can be perceived that the tablet has to have alread…
Preparation of Molar and Normal Solutions
Molar and
normal solutions are used in the chemical analysis of raw materials. A specific
amount of chemical (solute) is dissolved to obtain the solution of required concentration
(molar or normal solutions).
How Sterilization of Parenteral Products is done by Radiation?
There are many different routes through which pharmaceutical products i.e drugs, medicinal chemical, fluids etc. are administered into the body. The different ways through which drugs and other pharmaceutical products are administered into the body can be classified broadly into two simple categories. These two simple categories are enteral also known as gastrointestinal and parental.
Difference between GC and HPLC Techniques
Gas Chromatography and the High Performance Liquid Chromatography system are separation techniques used in obtaining specific eluents from an analyte basing on the compounds in the analyte distribution between the two phases (Mobile phase and Stationary phase). The mobile phase is the part in chromatography which moves and it usually contains the sample while the stationary phase is one which doe…
C18 HPLC Columns and Their Properties
Standards and success of any pharmaceutical company is determined by how professional chemical analysis are being undertaken. Chromatography remains the most important technique for identifying and analyzing a wide variety of chemical samples within pharmaceutical industries. The technique does not only help chemical analysis in scientifically analyzing compositions of various drugs during their …
Differences between HPLC and UPLC
Liquid chromatography is a technique that is utilized to separate any sample into its individual components. In this case, the chromatographic procedure involves a liquid as the moving phase. HPLC and UPLC stand for High Performance Liquid Chromatography and Ultra Performance Liquid Chromatography respectively.
Karl Fischer Reagent and Its Reactions
You are given a sample with a trace amount of water and you need to determine the amount of water in the sample, what do you do? The method to use is the Karl Fischer (KF) moisture analysis. Karl Fischer method uses the Karl Fischer Reagents to determine the moisture content of a sample and it is a widely popular method because it allows you to determine the water content of drug in a very fast, …
Electronic Batch Records in Pharmaceuticals
Traditionally, most pharmaceutical companies used hard copy records to keep production batch records commonly known as master production batch records. However, this documentation method has numerous shortcomings. In 1997, Electronic Batch records in Pharmaceuticals were accepted by FDA after EBR systems showed compliance with FDA regulations.
Occupational Exposure Bands (OEBs) for Chemicals
Occupational exposure bands are measures put in place to categorize chemicals so that the health of the worker is not compromised. This is because Active Pharmaceutical Ingredients can have serious and adverse effects on the worker when they become lowly airborne. They are usually classified on the potency of the exposure to the worker when exposed to the chemicals.
Types of Primary Packaging in Pharmaceuticals
Packaging is one of the most important parts of the pharmaceutical industry. The packaging ensures the protection of drug during the sale, storage, and use. Objectives of packaging are containment, physical and chemical protection, portion control, and security of the drug. Packaging in the pharmaceutical packaging companies at different levels i.e. primary, secondary and tertiary.
Packaging of Pharmaceutical Products
In the healthcare field, pharmaceutical packaging plays a vital role in keeping prescribed drugs and medication safe from all sorts of contamination and bacterial growth. Unlike other goods, pharmaceutical medicines require a much thorough inspection of their packaging so that they are completely safe for consumption by ill patients.
Causes and Remedies of Binding in Tablet Manufacturing
Tablet manufacturing involves a series of processes all aimed at the result of a uniform fine piece of art tablet. This article aims at exploring the causes and remedies of binding in tablet manufacturing. The processes include sizing, milling, drying, and compressing among several other procedures. Well, in each of the processes there are possibilities of defects that give rise to associated pro…
Difference between cGMP and GMP
Many people may question the real difference between current Good Manufacturing Process (cGMP) and Good Manufacturing Process (GMP). First off GMP is a set of guidelines, created by the Food and Drug Administration (FDA), that the pharmaceutical industry has put into place to guarantee the products are safe, pure and of great quality.
Difference between GMP and GLP
To the uninitiated, the difference between GMP and GLP can be a hard nut to crack. But as the names suggest, it is a no-brainer to unravel that they both concerned with laboratory testing and ensuring the safety and integrity of drugs and chemical products. These terminologies often confuse many people and it is about time that we shed some light on what they really entail.
Causes and Remedies of Sticking in Tablet Manufacturing
The tablet production process has become more simplified and more mechanized with the development of technology. However, the complexity of a tablet punching process has increased. But relatively the problems associated with the tablet manufacturing process have not yet been significantly reduced.
