Structure and Uses of Ethyl Chloride, Chloroform, Trichloroethylene, Tetrachloroethylene : Pharmaguideline -->

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Structure and Uses of Ethyl Chloride, Chloroform, Trichloroethylene, Tetrachloroethylene

C2H5Cl is the chemical formula for ethyl chloride. Among the chloroethanes, chloroethane is the simplest and least toxic member.

Ethyl chloride


C2H5Cl is the chemical formula for ethyl chloride. Among the chloroethanes, chloroethane is the simplest and least toxic member, i.e., ethane in which a chlorine has replaced one hydrogen. It is a colourless gas that has a boiling point of 12°C, is used as a topical anesthetic (hence the name), in the treatment of sports injuries and in ear piercings and skin biopsies. The chemical had previously been used for the production of tetraethyllead. Among its functions are inhalation anaesthesia, local anaesthesia, and antipruritic.


Ethyl chloride is commonly used to produce tetraethyllead (TEL). Other commercial applications included using it as a chemical reagent. Commercial ethyl cellulose is still made by treating cellulose with this compound. Diagnosis of a dead tooth with no pulp is done with ethyl chloride.
  • Sports injuries and muscular pain can be relieved with it.
  • An area of the skin is numbed with it before a procedure is performed.



Initially, chloroform was employed as an anesthetic due to its organic chemical properties. Chloroform was first synthesized in 1831. Chloroform is composed of hydrogen chloride and chlorine (CHCl3). A thick liquid, it has a sweet smell and has no color. When drinking water, wastewater, or swimming pools are chlorinated, chloroform may be released into the air. Lacrimator chemicals, such as chloroform, are industrial chemicals. Non-flammable characteristics make it a safer substance to handle than ethanol.


  • Anaesthetics are used in root canals during dentistry as an anaesthetic.
  • Chromatographic analysis is done by first analyzing the spectrum of pure chloroform as a reference or background, and then dissolving pure cholesterol powder or cholesterol extract from milk products in a chloroform solution and FTIR analyzing the results.
  • Traditionally, chloroform was used as a solvent for removing fats, greases, oils, and other substances; as a laundry detergent.
  • The product is used in adhesives and as a component of food contact materials in packaging and food packaging materials.



With a molecular formula of C2HCl3, trichloroethylene (TCE) is known by its IUPAC name of trichloroethylene (TCE). Transparent, colorless, mobile, and smelling like ether, this liquid is transparent and mobile.

In 1864, trichloroethylene was produced for the first time. As a man-made substance, it is not found in the natural atmosphere. Processes, transportation, and consumption are main sources of trichloroethylene emissions. In addition to its release during evaporation from and during the manufacture of paints, adhesives, and coatings, it may also be released during evaporation from adhesive glues.


  • The fluorocarbon refrigerants which are made using TCE are used in the refrigeration industry.
  • Machinery and equipment parts were degreased with TCE as an effective degreaser. Generally used as a solvent (trichloroethylene solvent) for removing grease from metal fabrications and certain textiles.
  • The use of trichloroethylene in the military has also been for cleaning kerosene-fueled rocket engines.
  • A component of adhesives, paint removers, typewriter correction fluids, and spot removers, it is also used in these products as an additive.
  • Removing residual water is required for the production of 100 percent ethanol.



C2Cl4 is the molecular formula of tetrachloroethylene, an organic chemical compound. In addition, perchloroethylene is also known as tetrachloroethylene. The substance is widely used in dry cleaning, which is why it has the name 'dry cleaning fluid'. Around 1 million tons of dry cleaning fluid were produced worldwide in 1985. Having a carbon-carbon double bond and halogen atoms, it belongs to the halogen alkene family. Tetrachloroethene is known by its IUPAC name. PERC or PCE are abbreviations of the acronym. Scientist Michael Faraday was the first to synthesize it in 1821. The hexachloroethane (C2Cl6) was used to synthesize it. Tetrachloroethylene can be expressed as Cl2C=CCl2, a chlorocarbon.


  • 1,1,1,2 Tetrachloroethane and hookworm infestation were historically treated with it as intermediates. Nowadays, it is used in many different fields for a variety of purposes. Below are just a few examples:
  • Fabrics are widely cleaned using this method. Dry cleaning fluid is part of its name.
  • Many organic materials can be dissolved in it in a variety of reactions.
  • Grease is removed from metal parts of automotive and other metal industries using this solvent.
  • In addition to being a cleaning agent, it can also be used with other chlorocarbons.
  • In paint strippers and spot removers, it is one of the ingredients.
  • Aerosol preparations contain it as well.
  • In physics, tetrachloroethylene is used in neutrino detectors for studying neutrinos.
  • The chemical is used in small quantities to remove vermin.
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Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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