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Sweetening Agents used in Oral Pharmaceutical Suspensions

Pharmaceutical companies rely on a variety of sweetening agents to make their oral pharmaceutical suspensions more palatable to patients.
Pharmaceutical companies rely on a variety of sweetening agents to make their oral pharmaceutical suspensions more palatable to patients. These sweetening agents can be made from a variety of sources, including sugar, aspartame, saccharin, and sucralose. What are the health risks associated with these sweeteners?

Oral pharmaceutical suspensions are a type of oral medication that is designed to be taken by mouth. Oral pharmaceutical suspensions are often made up of a combination of sweeteners, diluents, and other ingredients. Sweeteners are used to make the medication more palatable, and to increase its shelf life. Diluent is used to make the medication more fluid, and to reduce the likelihood of it clumping together in the stomach. Other ingredients may be used to improve the flavor or texture of the suspension.

Sweetening agents are often used in oral pharmaceutical suspensions because they help make the medication more palatable and easier to take by mouth. Sweetening agents can also help increase the shelf life of the suspension, and improve its flavor and texture.
Related: Oral Liquid Pharmaceutical Dosage Forms

Sweetening Agents Used in Oral Pharmaceutical Suspensions

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The sweetening agent used in oral pharmaceutical suspensions is a topical anesthetic. The sweetening agent is used to make the oral suspension more palatable. Sweetening agents are also used to reduce the bitterness of the medication.

There are several types of sweetening agents that can be used in oral pharmaceutical suspensions. These include sugar, saccharin, aspartame, neotame and acesulfame potassium.

Sugar is the most common sweetening agent used in oral pharmaceutical suspensions. Sugar is a natural sugar found in many foods and beverages. Saccharin is a man-made sugar substitute that is also known as Sweet and Low or Equal. Aspartame is a low-calorie artificial sweetener that is made by combining two amino acids - aspartic acid and phenylalanine - into a molecule that resembles glucose. Neotame is a synthetic version of aspartame that has been modified so it does not break down in the body. Acesulfame potassium is an artificial sweetener that is also known as Ace-K or Sunett.

Using different types of sweetening agents can affect the sweetness, bitterness and calories in an oral pharmaceutical suspension. Saccharin, aspartame and neotame are the most sweetening agents, while acesulfame potassium is the least sweet. Saccharin, aspartame and neotame have about the same level of sweetness, while acesulfame potassium is slightly less sweet.
Related: Differences between Syrups and Suspensions

Risks Associated with Sweetening Agents

Sweetening agents are typically used in oral pharmaceutical suspensions to make them more palatable. However, some sweetening agents have been linked to health risks, including cancer.

Some sweetening agents, such as aspartame, are known to cause cancer in animals. Other sweetening agents, such as saccharin, may also pose health risks. Although the safety of these agents has not been fully studied in humans, it is important to be aware of the potential risks associated with using them.

There are many sweetening agents used in oral pharmaceutical suspensions, and many of these agents have been linked to serious health risks. As such, it is important to be familiar with the different types of sweetening agents and their potential side effects before using them in your pharmacy. By doing so, you can make sure that you are providing your patients with the best possible medication experience.





Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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