Proper execution of protocol is an important part of the validation process. Execution of validation protocol affects the validation results. There should be minimum deviations during the validation process.
Jul 13, 2014
A protocol is a written statement to conduct the validation process along with the procedure, test method, equipment handling, specifications, acceptance criteria, report and approval.
Jul 11, 2014
Routes of administration of a drug is determined by its physical and chemical properties, patient characteristics and the rapidity of response desired. Major routes are oral, parenteral and topical.
Jul 7, 2014
A drug is defined as a substance used for diagnosis, prevention and treatment of disease. A dosage form of a drug is a product suited for administration to the patient by various routes for diagnosis or treatment of disease. Suitable dosage forms are needed for protection of the drug from destructive influences of the atmospheric oxygen or moisture, for protection of drug from destruction from gastric acid on oral administration, to mask bitter taste and foul odour, to provide extended drug action through controlled release mechanism etc. Following agents are used with drug for suitable dosage form.
Jul 1, 2014
Good documentation practice GDP is a systematic procedure of preparation, reviewing, approving, issuing, recording, storing and archival of any document.
Jun 29, 2014
Jun 23, 2014
Blend uniformity is an important factor in pharmaceutical manufacturing. A poor uniformity of the blend can cause the rejection of the product that can lead to the loss of revenue.
Jun 15, 2014
Chiral molecules are able to rotate the plane polarized light and this quality of these molecules is known as optical activity. Optical activity is measured by polarimeter. Polarimeter has a light source, polarizing filter, sampling tube and analyzing lens. Molecules having optical activity are known as optically active molecules.
Jun 8, 2014
The purpose of an audit trail is to make the electronic data secure and traceable. Audit trail is a regulatory requirement in pharmaceutical manufacturing. Audit trail shows in record the name of persons who assessed the computer system with the date and time. It also helps to recover the lost data.
May 26, 2014
Depyrogenation is the removal of pyrogen (endotoxins) from the pharmaceutical materials or equipments. Endotoxins are the lipopolysaccharides found in the cell walls of the gram negative bacteria. Pyrogen causes fever when enter in bloodstream.
May 18, 2014
Buying medicines online through internet can save your time and sometimes money. But you should be careful when ordering the prescription medicines online.
May 14, 2014
May 5, 2014
Validation is a documented evidence of the consistency of any process or system. It was firstly appeared in 1978 in United States by the Food and Drug Administration (FDA) to investigate the failure of the product in sterility and now it is very common concept in the pharmaceutical industries throughout the world.
Apr 28, 2014
Apr 18, 2014
Quality of pharmaceutical products majorly depends upon the sampling of the excipents and the active pharmaceutical ingredients. Proper sampling can give us confidence in our analysis. In other words we can say – sampling is a starting process but is has its importance.
Apr 13, 2014
Pass box is used to transfer the material from lower cleanliness area to higher cleanliness area or vice-versa in classified area and also known as hatch. Pass box works as a barrier between two cleanliness level areas.
Apr 6, 2014
Temperature and humidity are important factors in the stability of the pharmaceutical ingredients. Temperature sensitive materials can degrade at higher temperature therefore it important to validate the storage area for temperature.
Mar 30, 2014
Mar 23, 2014
Mar 19, 2014
Mar 10, 2014
Branded medicines are very costly due to the additional cost for the brand promotion. There are a lot of generic alternatives for these costly branded medicines. This can help to save money for the same medicines.
Mar 2, 2014
There is a big difference in the prices of the pharmaceutical products in India. The products having same drugs with same label claim are being sold in different prices. Sometimes this difference increases the prices twice, thrice or even ten folds.