Preparation and Standardization of 0.02 M Cupric Sulphate : Pharmaceutical Guidelines

Preparation and Standardization of 0.02 M Cupric Sulphate

Preparation and standardisation of 0.02 M Cupric Sulphate solution using Disodium Edetate and Pyridylazonaphthol solution as indicator that is used in pharmaceutical analysis.

Cupric Sulphate Solution Preparation

•  Dissolve 5.0 g of cupric sulphate in water and dilute to 1000 ml with water.
•  Standardize the solution in the following manner.


Cupric Sulphate Solution Standardization

•  To 20.0 ml add 2 g of sodium acetate.
•  Titrate with 0.02 M disodium edetate, using 0.1 ml of pyridylazonaphthol solution as indicator, until the color changes from violet-blue to bright green, adding the titrant slowly towards the end-point.
•  1 ml of 0.02 M disodium edetate is equivalent to 0.004994 g of CuSO4.5H2O.

Also see: Determination of Shelf Life of Solutions in Laboratory




Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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