Preparation and standardisation of 0.02 M Cupric Sulphate solution using Disodium Edetate and Pyridylazonaphthol solution as indicator that is used in pharmaceutical analysis.
Cupric Sulphate Solution Preparation
- Dissolve 5.0 g of cupric sulfate in water and dilute to 1000 ml with water.
- Standardize the solution in the following manner.
Cupric Sulphate Solution Standardization
- To 20.0 ml add 2 g of sodium acetate.
- Titrate with 0.02 M disodium edetate, using 0.1 ml of pyridylazonaphthol solution as an indicator, until the color changes from violet-blue to bright green, adding the titrant slowly towards the end-point.
- 1 ml of 0.02 M disodium edetate is equivalent to 0.004994 g of CuSO4.5H2O.
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Determination of Shelf Life of Solutions in Laboratory
Dr. Ankur Choudhary is a prominent Pharmaceutical Quality Assurance expert, consultant and the founder of Pharmaguideline. With over 22 years of hands-on experience in cGMP-compliant manufacturing environments, he specializes in establishing validation protocols, sterile area controls and data integrity systems. Ankur routinely interprets international regulatory frameworks (including FDA, EMA and ICH guidelines) to help global pharmaceutical professionals ensure strict regulatory compliance and operational excellence. Connect with Ankur on LinkedIn. Need Help: Ask Question
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