Preparation and Standardization of 0.5 M Potassium Hydroxide in Ethanol (60 %) : Pharmaceutical Guidelines

Preparation and Standardization of 0.5 M Potassium Hydroxide in Ethanol (60 %)

Preparation and standardisation of 0.5 M Potassium Hydroxide in 60 % ethanol using Hydrochloric Acid and Phenolphthalein solution as indicator used in pharmaceutical analysis.

Potassium Hydroxide in Ethanol Solution Preparation

•  Dissolve 30 g of potassium hydroxide in sufficient ethanol (60 %) to produce 1000 ml.
•  Standardize the solution in the following manner.

Potassium Hydroxide in Ethanol Solution Standardization

•  Pipette 20.0 ml of standardize 0.5 M hydrochloric acid into a flask.
•  Add 0.1 ml of phenolphthalein solution.
•  Titrate with the ethanolic potassium hydroxide solution until permanent pale-pink color is produced.
•  1 ml of 0.5 M hydrochloric acid is equivalent to 0.02806 g of KOH.

Also see: Determination of Shelf Life of Solutions in Laboratory




Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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