Preparation and Standardization of 0.1 M Ethanolic Potassium Hydroxide : Pharmaceutical Guidelines

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Preparation and Standardization of 0.1 M Ethanolic Potassium Hydroxide

Preparation and standardisation of 0.1 M Ethanolic Potassium Hydroxide using Hydrochloric acid and Phenolphthalein solution used for pharmaceutical analysis.

Ethanolic Potassium Hydroxide Solution Preparation

  • Dissolve about 6 g of potassium hydroxide in 5 ml of water.
  • Add sufficient aldehyde-free ethanol (95 %) to produce 1000 ml.
  • Allow the solution to stand in a tightly-stoppered bottle for 24 hours.
  • Then quickly decant the clear supernatant liquid into a suitable, tightly-closed container.
  • Standardize the solution in the following manner.

Ethanolic Potassium Hydroxide Solution Standardization

  • Pipette 20.0 ml of 0.1 M hydrochloric acid into a flask.
  • Dilute with 50 ml of water and add 0.1 ml of phenolphthalein solution.
  • Titrate with the ethanolic potassium hydroxide solution until a permanent pale pink color is produced.
  • Store protected from light and moisture.
  • 1 ml of 0.1 M hydrochloric acid is equivalent to 0.00561 g of KOH.
Also see: Determination of Shelf Life of Solutions in Laboratory





Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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