Preparation and Standardization of 0.5 M Potassium Hydroxide in Ethanol (60 %) : Pharmaguideline

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Preparation and Standardization of 0.5 M Potassium Hydroxide in Ethanol (60 %)

Preparation and standardisation of 0.5 M Potassium Hydroxide in 60 % ethanol using Hydrochloric Acid and Phenolphthalein solution as indicator used in pharmaceutical analysis.

Potassium Hydroxide in Ethanol Solution Preparation

  • Dissolve 30 g of potassium hydroxide in sufficient ethanol (60 %) to produce 1000 ml.
  • Standardize the solution in the following manner.

Potassium Hydroxide in Ethanol Solution Standardization

  • Pipette 20.0 ml of standardize 0.5 M hydrochloric acid into a flask.
  • Add 0.1 ml of phenolphthalein solution.
  • Titrate with the ethanolic potassium hydroxide solution until the permanent pale-pink color is produced.
  • 1 ml of 0.5 M hydrochloric acid is equivalent to 0.02806 g of KOH.
Also see: Determination of Shelf Life of Solutions in Laboratory

Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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