Preparation and Standardization of 0.1 M Lead Nitrate : Pharmaguideline

Online GMP Courses with Certificate


Preparation and Standardization of 0.1 M Lead Nitrate

Preparation and standardisation of 0.1 M Lead Nitrate solution using Disodium Edetate and Xylenol Orange mixture as indicator used in chemical analysis of pharmaceutical ingredients.

Lead Nitrate Solution Preparation

  • Dissolve 33.12 g of lead nitrate in sufficient water to produce 1000 ml.
  • Standardize the solution in the following manner.

Lead Nitrate Solution Standardization

  • Pipette 50.0 ml of the solution into a flask.
  • Add 50 mg of xylenol orange mixture and sufficient hexamine to produce a violet-pink color.
  • Titrate with 0.1 M disodium edetate to a lemon yellow endpoint.
  • 1 ml of 0.1 M disodium edetate is equivalent to 0.03312 g of Pb(N03)2.
Also see: Determination of Shelf Life of Solutions in Laboratory

Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
.moc.enilediugamrahp@ofni :liamENeed Help: Ask Question

No comments:

Post a Comment

Please don't spam. Comments having links would not be published.

Popular Categories

QA SOPs QC SOPs Micro SOPs HVAC Production SOPs Stores SOPs Checklists Maintenance SOPs HPLC Sterile GLP Validation Protocols Water System GDP Regulatory Maintenance Calibration Warning Letters Education B.Pharmacy
Online Courses

Follow Pharmaguideline



Editable Pharmaceutical Documents in MS-Word Format. Ready to use SOPs, Protocols, Master Plans, Manuals and more...



Recent Posts