Preparation and Standardization of 0.1 M Silver Nitrate : Pharmaceutical Guidelines

Preparation and Standardization of 0.1 M Silver Nitrate

Preparation and standardisation of 0.1 M Silver Nitrate solution using Sodium Chloride and Eosin Y indicator.

Silver Nitrate Solution Preparation

  • Take about 100 ml of water in a cleaned and dried 1000 ml volumetric flask.
  • Add about 17 gm of Silver Nitrate with continues stirring. 
  • Add more about 700 ml of distilled water, mix.
  • Make up the volume 1000 ml with water. Mix solution thoroughly. 
  • Keep the solution for at least one hour and then carry out the standardization.
Related: Determination of Shelf Life of Solutions in Laboratory

Silver Nitrate Solution Standardization

  • Transfer about 50 mg, accurately weighed, of reagent-grade sodium chloride, previously dried at 110° for 2 hours, to a 150-ml conical flask.
  • Dissolve in 5 ml of distilled water. 
  • Add 2.5 ml of acetic acid, 25 ml of methanol, and about 0.25 ml of Eosin Y indicator.
  • Stir, preferably with a magnetic stirrer.
  • Titrate with the silver nitrate solution.
  • Calculate the molarity of solution by the following formula:
                  NaCl in mg
M = ---------------------------
           AgNO3 in ml x 58.44

Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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4 comments: Post Yours! Read Comment Policy ▼

  1. Is there other way of standardizing Silver Nitrate?

  2. Sir this method good but factor limit 0.95 to 1.05 na


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