Preparation and Standardization of 0.1 M Silver Nitrate : Pharmaceutical Guidelines

Preparation and Standardization of 0.1 M Silver Nitrate

Preparation and standardisation of 0.1 M Silver Nitrate solution using Sodium Chloride and Eosin Y indicator.

Silver Nitrate Solution Preparation:

•  Take about 100 ml of water in a cleaned and dried 1000 ml volumetric flask.
•  Add about 17 gm of Silver Nitrate with continues stirring.
•  Add more about 700 ml of distilled water, mix.
 Make up the volume 1000 ml with water. Mix solution thoroughly.
•  Keep the solution for at least one hour and then carry out the standardization.

Related: Determination of Shelf Life of Solutions in Laboratory

Silver Nitrate Solution Standardization:

•  Transfer about 50 mg, accurately weighed, of reagent-grade sodium chloride, previously dried at 110° for 2 hours, to a 150-ml conical flask.
•  Dissolve in 5 ml of distilled water. 
•  Add 2.5 ml of acetic acid, 25 ml of methanol, and about 0.25 ml of Eosin Y indicator.
•  Stir, preferably with a magnetic stirrer.
•  Titrate with the silver nitrate solution.
•  Calculate molarity of solution by following formula:

                NaCl in mg
M = ---------------------------
         AgNO3 in ml  x 58.44





Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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3 comments: Post Yours! Read Comment Policy ▼

  1. Is there other way of standardizing Silver Nitrate?

    ReplyDelete
    Replies
    1. What is the problem with this method.

      Delete
  2. Sir this method good but factor limit 0.95 to 1.05 na

    ReplyDelete

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