SOP for Sieve Analysis : Pharmaceutical Guidelines

SOP for Sieve Analysis

Standard operating procedure to perform the sieve analysis of various samples.


       To lay down procedure for sieve analysis.

2.0  SCOPE   

       This procedure is applicable for sieve analysis of various granules and in-process sample.


3.1  Doing      : Technical Assistant
3.2  Checking : Executive /Manager


       Head of the Department

5.0  PROCEDURE                        

5.1  Use 16, 20, 40 and 60 mesh sieve for sieve analysis.
5.2  Keep in ascending order on each other.
5.3  Weigh 10 to 15 gm of sample and put it on 16 mesh sieve.
5.4  Stir the granules with stainless steel spatula, so that granules above 16 mesh remains on the sieve and finer particles passes through 16 mesh sieve.
5.5  Note down the weight of finer particles retained above 20 mesh.
5.6  Weigh the granules retained above 40 mesh sieve and stir the granules with stainless steel spatula.
5.7  Note down the weight of granules collected above 60 mesh sieve and below 60 mesh sieve.
5.8  Calculate the percentage of granules collected below 16 mesh, between 16 to 20 mesh and between 20 to 40 mesh, between 40 to 60 and below 60 mesh sieve. Record the results.

Related: Different Mesh Sizes Used in Pharmaceuticals and Their Conversion


6.1  SOP - Standard Operating Procedure

Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of Pharmaceutical Guidelines, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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