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Preparation and Standardization of 0.05 M Barium Chloride

Preparation and standardisation of 0.05 M Barium Chloride solution using Disodium edetate and Metalphthalein as indicator used in pharmaceutical analysis.

Barium Chloride Solution Preparation

  • Dissolve 12.2 g of barium chloride in sufficient water to produce 1000 ml.
  • Standardize the solution in the following manner.

Barium Chloride Solution Standardization

  • To 10.0 ml of the solution add 60 ml of water, 3 ml of strong ammonia solution and 0.5 to 1 mg of metalphthalein as an indicator.
  • Titrate with 0.05 M disodium edetate. 
  • As the solution begins to decolorize, add 50 ml of ethanol (95 %) and titrate until the bluish violet color is discharged.
  • 1 ml of 0.05 M disodium edetate is equivalent to 0.012215 g of BaCl2.2H20.
Also see: Determination of Shelf Life of Solutions in Laboratory

Ankur Choudhary is India's first professional pharmaceutical blogger, author and founder of, a widely-read pharmaceutical blog since 2008. Sign-up for the free email updates for your daily dose of pharmaceutical tips.
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